Tissue Microarray?
The Tissue Microarray is a slide which contains numerous small tissue
sections of various types. The diameter of each spot section can range
from 0.6 to 2.0 mm and the sections can number from tens to several
hundreds. Each tissue section is extracted from various donor blocks
and transferred into a ready-made recipient block. The donor blocks
are generally conventional formalin-fixed paraffin-embedded blocks
but can also be different types, such as non-formalin-fixed, frozen,
etc.
What are the benefits?
¡æ Provides every feature of whole-tissue sections
For example, allows for observation
of Proteins, RNA and DNA
from almost the same region.
¡æ Saves you
£ª Time: a few days to even weeks or months
£ª Money: a few hundred to ten thousands of
dollars
£ª Labor: one experiment or several hundreds
¡æ Minimizes experimental errors caused by differing conditions
Who Needs
TMA?
¡æ Those hoping to
£ª Discover various molecular events or molecules
£ª Find candidates for novel molecular targets,
such as a
cancer gene
£ª Validate candidates for novel molecular
targets
using human tissue having a lot of necessary
information.
Why is
the PETAGEN array the best ?
¡æ Thorough quality control
¡æ Almost no loss of tissue spots
¡æ Maximum preservation of tissue antigenicity
¡æ Allows for detailed pathological and clinical information
¡æ Largest variety of organs that can fit on a single slide
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