→ Formalin-/Paraformaldehyde-fixed or frozen tissues
→ The ideal diameter for tissue section spot (1.0 mm)
→ Number of spots on a slide can be matched to a specific need
→ Easy-to-read format
→ Individually packed to maintain maximum antigenicity and prevent
oxidation
→ Relevant Information and Certificates →Top
1.Correct Sampling
of Tissues from
donors
2.Identicalness of
tissue processing
3.Materials used in
the process
1.Conducted by
certificated
pathologists and
technologists
2.Standardized and
strict protocol and
supervised by
certificated
pathologists
3.Using top-quality
materials
2. Selection of to-be-
punched
position on the donor block
1.Correctness of the
mapping
1.Conducted by
certificated
pathologists and
double checked
3. Punching the target
tissue core
1.Correctness and
preciseness of the
punching
2.Minimum damage
to the core and the
donor block
1-1. Guided by a
real time
magnified
image
1-2. Carried out
to minimize
errors
stemming
from manual
operation
2. Specially
designed needle
to guarantee the
smoothness of
margin of the
punched core
4. Making a hole into
which the punched core is going to be transferred
1.Punching needle
2.Punching process
3.Material used to
make the recipient
block
1.Specially designed
needle to
guarantee the
fitness of core to
the hole.
2. Carried out
to minimize errors
stemming from
manual operation
3. Using the
material which
was confirmed by
a lot of
experiments
regarding
hardness,
minimum crack
during the
process, ease
to etc.
5. Transfer of the core
into the hole Transfer of the core into the hole
Transfer process
Carried out to minimize errors stemming from manual
operation - automatic control of the position
6. Manufacturing of the
Tissue Microarray
1. Instruments and
materials such as
a microtomb,
a blade,
a base slide etc.
2. Sectioning and
transferring the
section onto
a base slide
1.Conducted by
certificated and
skillful
technologists
2.regularly checking
the instruments
and using
top-quality
materials
6. Packing the Tissue
Microarray
1.Packing method 2.Packing materials
1.Packed
individually
and twice with
two different
packing materials
under nitrogen
atmosphere to
prevent oxidation
and drying
2.Specially designed
packing materials:
a hard plastic box
and an opaque
bag
7. Others
1. Maintaining
seriality
1.All labels are
pre-attached to
the materials
before use and
all task carried
by two different
persons
simultaneously
② Quality Assurance Guide
To guarantee the correctness of each tissue spots on the Tissue Microarray,
1. Tissue Microarray every serial 20 ones and final section of
the Tissue Microarray block are H&E stained
and examined by
a certificated pathologist
2. Some randomly-selected H&E stained Tissue Microarrays among
the already read ones by a pathologist are
subject to be re-read
by another pathologist
3. All Tissue Microarrays go under the scrutiny of well trained
technologists before packing to guarantee no loss
of tissue spots
4. The state of being packed are individually checked by our
employees to check the existence of any defects
such as a leak.
→ Detailed pathological
and clinical information
Pathological
information
Gross examination
Histological H&E
Special Pathologic
study
Site of tumoTumor Type (gross
level)Depth of invasion
Chemo/Radiation therapy
Clinical laboratory data
Other diagnostic information
Clinical stage
Duration year
Survival period after surgery
Live or Dead
Cause of death
*In case of autopsy tissues, detailed clinical information
may not be available.
→ Reasonable
price range & maximum cost-effectiveness
Our 1 TMA slide can provide you with the following invaluable benefits
:
＊ the largest number of spots from individuals
＊ Detailed pathological and clinical data
providing many important facts about your
research →Top
